Other than, of course, pouring red bull on it.
Even if you're planning on driving, basic packing skills are necessary. Chances are good you don't have a whole lot of trunk space (and even if you do, you should fill it with friends and their stuff and have a fabulous road trip).
1. Roll your clothes! This will give you lots more space. Fold them longways and then roll them up and stuff them into your suitcase.
2. Fill your shoes with socks--don't waste empty places!
3. Spread out your heavy stuff. Having one suitcase full of textbooks and clunky heels and one full of fluffy sheets and pillows will mean that you have 100 lbs total, spread out 98 to 2. This is not ideal for your buff friend carrying the suitcase or for trying to get it into the air.
4. Use the corners. Suitcases are usually rounded, but socks, underwear, and belts make very good suitcase stuffers. Again, again, and again, don't waste your space!!
5. Don't pack children. They usually grow to over 50 lbs once you reach your landing location. It's also frowned upon in most civilized societies (Texas excepted).
6. If you're driving, snacks ride up front with you. This not only leaves room for more junk in your trunk, but also gives you easy access to the most important thing you'll have with you.
7. For car packing, treat the corners of your trunk like the rounded corners of your suitcase. Stuff in sweatshirts, blankets, clothes, lamps, and roommates.
8. If you have a choice, make rolling suitcases your heavier bags rather than duffel bags just for the sake of making them easier to tote around (make sure you factor in the weight of the wheels though).
Follow these rules so that your entire room can look like this:
Just find someone to carry it to your car/the airport for you and you should be all set.